000 | 02672cam a2200265 a 4500 | ||
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001 | 17427719 | ||
005 | 20161108115010.0 | ||
008 | 120808t2013 njua frb 001 0 eng d | ||
020 | _a9780470942383 | ||
040 |
_aDNLM/DLC _cDLC _dDLC _dEG-ScBUE _beng |
||
082 | 0 | 4 |
_a615.19 _222 _bMAS |
245 | 0 | 0 |
_aMass spectrometry for drug discovery and drug development / _cedited by Walter A. Korfmacher. |
260 |
_aHoboken : _bJohn Wiley & Sons, _cc.2013. |
||
300 |
_axii, 461 p. : _bill. ; _c26 cm. |
||
500 | _aIndex : p. 427-461. | ||
504 | _aIncludes bibliographical references. | ||
505 | 0 | _a1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / Gerard Hopfgartner -- 2. Utility of high resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang -- 3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia -- 4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou -- 5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash -- 6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky -- 7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak -- 8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion -- 9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendra�y N. Pramanik -- 10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli -- 11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer -- 12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury -- 13. Mass spectrometry of siRNA / Mark Cancilla and Mike Flanagan -- 14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily -- 15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high resolution full scan? / Lieve Dillen and Filip Cuyckens. | |
650 | 7 |
_aDrugs _2BUEsh _939601 _xAnalysis. |
|
650 | 7 |
_aMass spectrometry _xmethods. _2BUEsh |
|
650 | 7 |
_aDrug development. _2BUEsh |
|
651 | _2BUEsh | ||
653 |
_bPPhrm _cNovember2016 |
||
700 | 1 |
_aKorfmacher, Walter A., _eeditor. |
|
942 | _2ddc | ||
999 |
_c23069 _d23041 |