000			02712cam a22003135a 4500
001			15417360
005			20151026135042.0
008			080814t2009 njua frb 001 0 eng d
020			_a9780470225554 (cloth)
020			_a0470225556 (cloth)
040			_aDNLM/DLC _cDLC _dNLM _dBAKER _dBTCTA _dYDXCP _dC#P _dBWX _dIXA _dDLC _dEG-ScBUE _beng
082	0	4	_a615.19 _222 _bDRU
245	0	0	_aDrug efficacy, safety, and biologics discovery : _bemerging technologies and tools / _c[edited by] Sean Ekins, Jinghai J. Xu.
260			_aHoboken : _bJohn Wiley & Sons, _cc.2009.
300			_axvi, 408 p. : _bill. (some col.) ; _c25 cm.
490	0		_aWiley series on technologies for the pharmaceutical industry
500			_aIndex : p. 381-408.
504			_aIncludes bibliographical references.
505	0		_aFocus on the fundamentals : toward better therapeutic index prediction / Jinghai J. Xu and Li J. Yu -- High-throughput protein-based technologies and computational models for drug development, efficacy, and toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, and Christopher W. Espelin -- Cellular systems biology applied to preclinical safety testing : a case study of CellCiphr profiling / Lawrence Vernetti ... [et al.] -- Systems pharmacology, biomarkers, and biomolecular networks / Aram S. Adourian ... [et al.] -- Zebrafish models for human diseases and drug discovery / Hanbing Zhong, Ning-Ai Liu, and Shuo Lin -- Toxicity pathways and models : mining for potential side effects / Sean Ekins and Josef Scheiber -- Computational systems biology modeling of dosimetry and cellular response pathways / Qiang Zhang ... [et al.] --
505	0		_aStem cell technology for embryotoxicity, cardiotoxicity, and hepatotoxicity evaluation / Julio C. Davila ... [et al.] -- Telemetry technology for preclinical drug discovery and development / Yi Yang --Nanotechnology to improve oral drug delivery / Mayank D. Bhavsar, Shardool Jain, and Mansoor M. Amiji -- Functional glycomics and the future of glycomic drugs / Ram Sasisekharan and Karthik Viswanathan -- Modeling efficacy and safety of engineered biologics / Jeffrey R. Chabot and Bruce Gomes -- Regulation of gene expression by small, non-coding RNAS : practical applications / Roman Herrara and Eric Tien -- Future perspectives of biological engineering in pharmaceutical research : the paradigm of modeling, mining, manipulation, and measurements / Jinghai J. Xu ... [et al.].
650		0	_aPharmaceutical technology _2BUEsh
650		0	_aBiological products _2BUEsh
651			_2BUEsh
653			_bPPhrm _cOctober2015
655			_vReading book _934232
700	1		_aEkins, Sean, _eeditor.
700	1		_aXu, Jinghai J., _eeditor.
942			_2ddc
999			_c20990 _d20962