TY - BOOK AU - Silverman,Richard B. AU - Holladay,Mark W. TI - The organic chemistry of drug design and drug action / SN - 9780123820303 (alk. paper) U1 - 615.19 22 PY - 2014/// CY - San Diego PB - Academic Press / Elsevier, KW - Pharmaceutical chemistry KW - BUEsh KW - Bioorganic chemistry KW - Molecular pharmacology KW - Drugs KW - Design KW - PPhrm KW - July2015 KW - January2016 KW - February2016 N1 - Index : p. 507-517; Includes appendix; Includes bibliographic references.; Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems ER -